Histamine Digest

(Formerly Histamine Block)

Histamine Digest™ by Seeking Health contains a patented enzyme formula providing 10,000 HDU of diamine oxidase (DAO) - the main enzyme responsible for the degradation of ingested histamine - per capsule. Histamine is known as a biogenic amine, an organic nitrogen compound, involved in certain immune responses and found in mast cells. It may be involved in regulating healthy function in the GI tract as well as the nervous system.

 Histamine also plays an important role in triggering the body’s normal inflammatory response. An excess of histamine can be problematic, however, leading to histamine sensitivity/intolerance, digestive concerns, allergies, and more. Individual sensitivity to histamine varies, and some individuals may be more reactive to histamines and other biogenic amines in foods.

Diamine oxidase (DAO) has been clinically tested and found to break down food-derived histamine in the digestive tract. Note that DAO is not absorbed and does not have systemic activity. Histamine Block does not manage or address antibody-related or IgE-related food allergies.*

Suggested Use:
Take 1 capsule no more than 15 minutes before the consumption of histamine-rich foods, or take as directed by your healthcare professional.


Serving Size: 1 Capsule

Amount Per Serving
DAO2™ porcine kidney extract ... 4.2mg
(Diamine Oxidase Activity 30,000 HDU)

Other Ingredients: Microcrystalline cellulose, vegetarian capsule (hypromellose, water, and gellan gum), and ascorbyl palmitate

NOT suitable for vegans or vegetarians

Free of: Eggs, Fish, Gluten, GMO, Milk, Peanuts, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, Artificial Flavors, and Artificial Preservatives